- Safe & Vault, Safford
- Safety Equipment & Supplies, Safford
- Sandwich Shop Restaurants, Safford
- Satellite Descrambling & Programming Service, Safford
- Satellite Dish Antennas & Equipment Dealers, Safford
- Satellite TV Service, Safford
- Sawmill, Paper & Woodworking Supplies, Machinery & Equipment, Safford
- Scrap & Waste Machinery, Safford
- Scrap & Waste Materials, Safford
- Screen Printing, Safford
- Secondary Schools, Safford
- Security Brokers & Dealers, Safford
- Security Investigative Services, Safford
- Security Services, Safford
- Senior Citizens Service & Health Organizations, Safford
- Septic Tank Installation & Repair, Safford - Septic Systems
- Septic Tank Pumping & Cleaning, Safford - Septic Systems
- Septic Tanks & Septic Systems Contractors, Safford - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Septic Tanks & Systems Contractors & Designers, Safford
- Sewer & Drain Cleaning & Repair, Safford - Drain Cleaner & Installation Services
- Sewing & Yarn Stores & Supplies, Safford
- Sewing Machine Repair & Service, Safford
- Sharpening Service, Safford
- Sheet Metal Contractors, Safford - Sheet Metal Fabrication
- Sheet Metal Fabricators & Ductwork Contractors, Safford
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- Shoe Store - More, Safford
- Shoe Stores, Safford - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Safford
- Signs, Safford
- Small Appliances, Safford
- Small Business & Office Equipment Repair Services, Safford
- Snacks & Desserts, Safford
- Social Services & Welfare, Safford
- Special Coatings, Safford - Protective Coatings
- Special Interest Schools Or Instruction, Safford
- Specialty Stores, Safford
- Speech & Hearing Specialists, Safford
- Sporting Goods Stores, Safford
- Staffing & Support Services, Safford
- Stamp Collecting & Coin Dealers , Safford
- State Government, Safford
- Steak House Restaurants, Safford
- Steel Buildings, Safford
- Steel Work Contractors, Safford
- Stereo, Audio & Video Equipment Dealers & Stores, Safford
- Stitching Services, Safford
- Stocks & Bond Brokers, Safford
- Surveyor Services, Safford - Surveying Service
- Swimming Pools Repair, Service, Supplies, Sale & Installation, Safford
- Swimming Pools Supplies, Equipment & Accessories, Safford
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